Tranexamic acid and it's uses in pre-hospital an emergency medicine Research Paper

Tranexamic acid and it's uses in pre-hospital an emergency medicine - Research Paper Example The acid should not be used because it works against clots and hence activates intravascular coagulation and platelet usage. If a person with DIC is administered with the acid they end up having end-organ damage due to microvascular pathologies. The unwanted effects of the drug include nausea, vomiting, diarrhea, hypotension and disturbances in vision. Tranexamic acid is used topically. The acid is excreted in the urine (Twycross et al, 2002). Tranexamic acid has lately been used in emergency medical scenarios. Even though hemostatic dressings and tourniquets have prevented conditions such as hemorrhagic shock, the usage of tranexamic acid can have the same effect. This drug has been used for a long time in cardiac surgeries and bleeding disorders such as hemophilia. Now it is being used in taking care of hemodynamic conditions. A study by the name of Clinical Randomization of an Antifibrinolytic in Significant Hemmorrhage 2 (CRASH-2) tested 20000 patients with tranexamic acid across various countries. The results of the study showed that in an emergency trauma center where patients had serious bleeding, tachycardia and hypotension were given tranexamic acid. The recipients of TXA had a mortality of 14.5 %. Hence patients receiving TXA were at benefit. Another study is the Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) was carried out which involved TXA infusion in an out-patient hospi tal. Tranexamic acid was administered in patients in which hemorrhagic shock was suspected. The results of the MATTERs study showed that individuals who received TXA had a mortality of 17.4% (Goodloe, 2013). Annually more than 500000 women lose their lives to postpartum events such as childbirth. Obstetric hemorrhage cause increased rates of maternal mortality. Hence systemic fibrinolytic agents are used in surgeries to prevent fibrinolysis to avoid blood loss after surgeries. A study

Technical Review 2 Research Paper Example | Topics and Well Written Essays - 1000 words

Technical Review 2 - Research Paper Example This paper is a technical analysis of a new technology referred as Bitcoin. The paper seeks to discern how Bitcoin can support cyber security challenges already in place. At the very end, the paper will analyze potential loopholes for exploitation and misuse and give a way forward. Of late there has been a lot of buzz concerning electronic currencies and other virtual monies. According to (Kregel, 2010) there is great potential in shifting towards electronic funds or web cash. The web cash system is at the inception stage and given the level of activity accompanying it, it is expected to reach the maturity phase in a couple of years. JPMorgan has already submitted a patent which seems to set new stage for competition among the already well known players such as Bitcoin (Reardon, 2012). The patented technology referred as JPMorgan Chase, is a new paradigm that facilitate the creation of a new virtual cash accounts with real time digital exchange value. It works by exchanging real time digital exchange information without the involvement of third parties such as banks. The structural components of the system include a Payment Portal Processor or a digital wallet, an Internet Pay Anyone IPA account, a virtual private Lockbox, EFT network, a cash card and an Accou nt Reporter (Reid, 2013). It works by exchanging digital information in a real time basis with capabilities to archive all the transactions in a personal digital wallet. With advanced built in security features involving crypto-currency models, transactions are safeguarded against vulnerabilities and attacks (Verme, 2013). According to the International Journal of Community Currency and Research, other electronic digital monies and crypto-currencies have emerged over time since the turn of the decade (Ryan, 2012). Infinitecoin hit the market in 2013 and though it offers an easy adjustment rate, it offers a broad spectrum. Quark coin launched almost the same time and